Ontology highlight
ABSTRACT:
SUBMITTER: Shao M
PROVIDER: S-EPMC5369966 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Shao Ming M Ge Guang-Zhe GZ Liu Wen-Jing WJ Xiao Ji J Xia Hou-Jun HJ Fan Yu Y Zhao Feng F He Bao-Li BL Chen Ceshi C
Oncotarget 20170301 10
Krüppel-like factors (KLFs) are a family of zinc finger transcription factors regulating embryonic development and diseases. The phylogenetics of KLFs has not been studied in tree shrews, an animal lineage with a closer relationship to primates than rodents. Here, we identified 17 KLFs from Chinese tree shrew (Tupaia belangeri chinensis). KLF proteins are highly conserved among humans, monkeys, rats, mice and tree shrews compared to zebrafish and chickens. The CtBP binding site, Sin3A binding si ...[more]