Ontology highlight
ABSTRACT:
SUBMITTER: Matsuda S
PROVIDER: S-EPMC5370161 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Matsuda Shinji S Movila Alexandru A Suzuki Maiko M Kajiya Mikihito M Wisitrasameewong Wichaya W Kayal Rayyan R Hirshfeld Josefine J Al-Dharrab Ayman A Savitri Irma J IJ Mira Abdulghani A Kurihara Hidemi H Taubman Martin A MA Kawai Toshihisa T
Journal of immunological methods 20160830
Using a mouse model of silk ligature-induced periodontal disease (PD), we report a novel method of sampling mouse gingival crevicular fluid (GCF) to evaluate the time-dependent secretion patterns of bone resorption-related cytokines. GCF is a serum transudate containing host-derived biomarkers which can represent cellular response in the periodontium. As such, human clinical evaluations of PD status rely on sampling this critical secretion. At the same time, a method of sampling GCF from mice is ...[more]