Ontology highlight
ABSTRACT:
SUBMITTER: Landrith TA
PROVIDER: S-EPMC5372813 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Landrith Tyler A TA Sureshchandra Suhas S Rivera Andrea A Jang Jessica C JC Rais Maham M Nair Meera G MG Messaoudi Ilhem I Wilson Emma H EH
Frontiers in immunology 20170329
During chronic infection, memory T cells acquire a unique phenotype and become dependent on different survival signals than those needed for memory T cells generated during an acute infection. The distinction between the role of effector and memory T cells in an environment of persistent antigen remains unclear. Here, in the context of chronic <i>Toxoplasma gondii</i> infection, we demonstrate that a population of CD8 T cells exhibiting a tissue-resident memory (T<sub>RM</sub>) phenotype accumul ...[more]