Ontology highlight
ABSTRACT:
SUBMITTER: Liu X
PROVIDER: S-EPMC5373589 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Liu Xiao X Wang Bao-Jin BJ Xu Luo L Tang Hong-Ling HL Xu Guo-Qing GQ
PloS one 20170330 3
Genes that are indispensable for survival are essential genes. Many features have been proposed for computational prediction of essential genes. In this paper, the least absolute shrinkage and selection operator method was used to screen key sequence-based features related to gene essentiality. To assess the effects, the selected features were used to predict the essential genes from 31 bacterial species based on a support vector machine classifier. For all 31 bacterial objects (21 Gram-negative ...[more]