Unknown

Dataset Information

0

Ribosome Assembly in Trypanosomatids: A Novel Therapeutic Target.


ABSTRACT: In Liu et al., the authors present a 2.5-Å structure of the Trypanosoma cruzi 60S ribosomal subunit and propose a model for the stepwise assembly of the large-subunit ribosomal RNA (rRNA). Based on this study, we discuss how the unique features of trypanosomatid ribosome assembly offer potential drug targets.

SUBMITTER: Kamina AD 

PROVIDER: S-EPMC5376504 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature

altmetric image

Publications

Ribosome Assembly in Trypanosomatids: A Novel Therapeutic Target.

Kamina Anyango D AD   Williams Noreen N  

Trends in parasitology 20161214 4


In Liu et al., the authors present a 2.5-Å structure of the Trypanosoma cruzi 60S ribosomal subunit and propose a model for the stepwise assembly of the large-subunit ribosomal RNA (rRNA). Based on this study, we discuss how the unique features of trypanosomatid ribosome assembly offer potential drug targets. ...[more]

Similar Datasets

| S-EPMC4929433 | biostudies-literature
| S-EPMC8990456 | biostudies-literature
| S-EPMC3356001 | biostudies-literature
| S-EPMC10952850 | biostudies-literature
| S-EPMC5650911 | biostudies-other
| S-EPMC8774031 | biostudies-literature
| S-EPMC6049871 | biostudies-other
| PRJNA549390 | ENA
| S-EPMC7835875 | biostudies-literature
| S-EPMC8898896 | biostudies-literature