Ontology highlight
ABSTRACT:
SUBMITTER: Li H
PROVIDER: S-EPMC5377547 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Li Haishan H Zhang Lingling L Jiang Quan Q Shi Zhenwang Z Tong Hanxing H
Experimental and therapeutic medicine 20170214 4
Familial adenomatous polyposis (FAP; Mendelian of Inherintance in Man ID, 175100) is a rare autosomal dominant disorder characterized by the development of numerous adenomatous polyps throughout the colon and rectum associated with an increased risk of colorectal cancer. FAP is at time accompanied with certain extraintestinal manifestations such as congenital hypertrophy of the retinal pigment epithelium, dental disorders and desmoid tumors. It is caused by mutations in the adenomatous polyposis ...[more]