Dataset Information

Circulating concentrations and relative percent composition of trans fatty acids in healthy Canadian young adults between 2004 and 2010: a cross-sectional study.

ABSTRACT:

Background

Trans fatty acids (TFAs) produced from industrial partial hydrogenation of vegetable oils have been the subject of much research regarding their negative effect on the development of chronic diseases, and recommendations to label foods with partially hydrogenated vegetable oils and limit their levels were introduced in Canada in 2003 and 2007, respectively. Our aim was to determine temporal changes in circulating plasma TFAs in a population of young healthy Canadian adults after the introduction of the guidelines.

Methods

In this study, circulating plasma concentrations and relative percent composition of individual TFAs over time (2004-2010) were determined in a cross-sectional cohort of young healthy Canadian adults as part of the Toronto Nutrigenomics study.

Results

A total of 1294 participants were included in the cohort. Relative to 2004, total TFA levels were significantly lower in 2005-2009 (p < 0.05), but not in 2010. Although levels of 16:1t9 and 18:1t11 declined after 2004, levels of 18:1t9 and 18:1t10 were significantly lower in 2005-2009 (p < 0.05), but not in 2010.

Interpretation

Trans fatty acids were lower in 2009 relative to 2004, but not different in 2010, suggesting that young Canadians may remain vulnerable to partially hydrogenated vegetable oil exposure and that there is a need for further monitoring of specific food categories and vulnerable populations.

SUBMITTER: Abdelmagid SA

PROVIDER: S-EPMC5378523 | biostudies-literature | 2017 Jan-Mar

REPOSITORIES: biostudies-literature

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Publications

Circulating concentrations and relative percent composition of trans fatty acids in healthy Canadian young adults between 2004 and 2010: a cross-sectional study.

Abdelmagid Salma A SA Nielsen Daiva E DE Badawi Alaa A El-Sohemy Ahmed A Mutch David M DM Ma David W L DW

CMAJ open 20170101 1

<h4>Background</h4>Trans fatty acids (TFAs) produced from industrial partial hydrogenation of vegetable oils have been the subject of much research regarding their negative effect on the development of chronic diseases, and recommendations to label foods with partially hydrogenated vegetable oils and limit their levels were introduced in Canada in 2003 and 2007, respectively. Our aim was to determine temporal changes in circulating plasma TFAs in a population of young healthy Canadian adults aft ...[more]

PMID: 28401129

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Project description:BackgroundThe increased use of high-oleic oils to replace trans fat has led to concern about declining intake of PUFA and the potential for essential fatty acid insufficiency or even deficiency.ObjectivesThe aim of this study was to examine circulating concentrations of essential and poorly biosynthesized fatty acids, as biomarkers of dietary intake, in the NHANES data sets prior to (2003-2004 cycle) and following (2011-2012 cycle) legislation to reduce trans fat in the food supply and also to explore the associations between these fatty acids and markers of cardiometabolic health.MethodsFasting circulating concentrations of fatty acids from adults (aged ≥20 y) in the 2003-2004 and 2011-2012 NHANES cycles were used for analysis. Dietary data from one day of both the 2003-2004 and 2011-2012 cycles were used to examine differences in dietary fatty acid intake between these cycles. Regression analyses were used to assess relations between circulating concentrations of fatty acids and cardiometabolic health.ResultsBetween 2003-2004 and 2011-2012, circulating concentrations of linoleic acid (LA) increased (1.38%, P = 0.002); no difference in dietary intake was observed. α-Linolenic acid (ALA), measured by dietary intake (0.14 g, P < 0.001) and circulating concentrations (0.23%, P < 0.01), increased from 2003-2004 to 2011-2012. Circulating LA was inversely associated with BMI (in kg/m2; regression coefficient per percentage point change in LA ± SE: -0.22 ± 0.04), waist circumference (-0.62 ± 0.09 cm), systolic blood pressure (-0.38 ± 0.09 mm Hg), triglycerides (-9.92 ± 0.63 mg/dL), glucose (-3.34 ± 0.13 mg/dL), insulin (-0.18 ± 0.05 µU/mL), and HOMA-IR (-0.29 ± 0.05).ConclusionsIn a nationally representative sample of US adults, no declines in circulating concentrations of essential fatty acids, LA and ALA, were observed between 2003-2004 and 2011-2012, a time when high-oleic oils were increasingly used in the food supply. Higher amounts of circulating LA were correlated with lower risk of cardiometabolic dysfunction, which underscores the importance of monitoring consumption in the United States.

Dataset Information

Circulating concentrations and relative percent composition of trans fatty acids in healthy Canadian young adults between 2004 and 2010: a cross-sectional study.

Background

Methods

Results

Interpretation

Publications

Circulating concentrations and relative percent composition of trans fatty acids in healthy Canadian young adults between 2004 and 2010: a cross-sectional study.

Similar Datasets

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