Breast tumor subgroups reveal diverse clinical prognostic power.
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ABSTRACT:
SUBMITTER: Liu Z
PROVIDER: S-EPMC5379255 | biostudies-literature | 2014 Feb
REPOSITORIES: biostudies-literature
Publications
Breast tumor subgroups reveal diverse clinical prognostic power.
Liu Zhaoqi Z Zhang Xiang-Sun XS Zhang Shihua S
Scientific reports 20140206
Predicting the outcome of cancer therapies using molecular features and clinical observations is a key goal of cancer biology, which has been addressed comprehensively using whole patient datasets without considering the effect of tumor heterogeneity. We hypothesized that molecular features and clinical observations have different prognostic abilities for different cancer subtypes, and made a systematic study using both clinical observations and gene expression data. This analysis revealed that ...[more]
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