Ontology highlight
ABSTRACT:
SUBMITTER: Malabanan MM
PROVIDER: S-EPMC5380233 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Malabanan M Merced MM Blind Raymond D RD
Biochemical Society transactions 20160201 1
Inositol polyphosphate multikinase (IPMK, ipk2, Arg(82), ArgRIII) is an inositide kinase with unusually flexible substrate specificity and the capacity to partake in many functional protein-protein interactions (PPIs). By merging these two activities, IPMK is able to execute gene regulatory functions that are very unique and only now beginning to be recognized. In this short review, we present a brief history of IPMK, describe the structural biology of the enzyme and highlight a few recent disco ...[more]