Ontology highlight
ABSTRACT:
SUBMITTER: Zhao X
PROVIDER: S-EPMC5381120 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Zhao Xiang X Zhao Gangsheng G Shi Zhongli Z Zhou Chenhe C Chen Yunlin Y Hu Bin B Yan Shigui S
Scientific reports 20170405
Previous studies have shown that Low intensity pulsed ultrasound(LIPUS) prevents polyethylene-debris-induced periprosthetic loosening in vivo, but the details of the mechanism by which it does so remain unclear. In this article, we used polyethylene debris induced RAW 264.7 cells as the in vitro model, and tested the effect of LIPUS on this model. Changes in the level of inflammatory cytokines, cell proliferation, and apoptosis were assessed. Gene overexpression and siRNA technique were applied, ...[more]