Ontology highlight
ABSTRACT:
SUBMITTER: Unekawa M
PROVIDER: S-EPMC5381456 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Unekawa Miyuki M Tomita Yutaka Y Masamoto Kazuto K Toriumi Haruki H Osada Takashi T Kanno Iwao I Suzuki Norihiro N
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20160721 2
Cortical spreading depression (CSD) induces marked hyperemia with a transient decrease of regional cerebral blood flow (rCBF), followed by sustained oligemia. To further understand the microcirculatory mechanisms associated with CSD, we examined the temporal changes of diameter of intraparenchymal penetrating arteries during CSD. In urethane-anesthetized mice, the diameter of single penetrating arteries at three depths was measured using two-photon microscopy during passage of repeated CSD, with ...[more]