Ontology highlight
ABSTRACT:
SUBMITTER: Diab A
PROVIDER: S-EPMC5382928 | biostudies-literature | 2013 Jan
REPOSITORIES: biostudies-literature
Diab Adi A Zickl Lynette L Abdel-Wahab Omar O Jhanwar Suresh S Gulam Manjit A MA Panageas Katherine S KS Patel Jay P JP Jurcic Joseph J Maslak Peter P Paietta Elisabeth E Mangan James K JK Carroll Martin M Fernandez Hugo F HF Teruya-Feldstein Julie J Luger Selina M SM Douer Dan D Litzow Mark R MR Lazarus Hillard M HM Rowe Jacob M JM Levine Ross L RL Tallman Martin S MS
Leukemia research 20121024 1
Previous small series have suggested that acute myeloid leukemia with t(8;16) is a distinct morphologic and clinical entity associated with poor prognosis. We describe 18 patients with t(8;16) AML, including their clinical, cytomorphologic, immunophenotypic and cytogenetic features. Half of the patients had extramedullary disease, most commonly leukemia cutis, which often preceded bone marrow involvement and six had therapy-related AML. Patients with t(8;16) AML commonly present with clinical an ...[more]