Ontology highlight
ABSTRACT:
SUBMITTER: Hutt JT
PROVIDER: S-EPMC5382964 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Organic chemistry frontiers : an international journal of organic chemistry 20160822 10
A new Pd-catalyzed alkene carboalkoxylation strategy for the preparation of 2,3-dihydrobenzofurans is described. This method effects the coupling of readily available 2-allylphenol derivatives with aryl triflates to generate a wide range of functionalized 2,3-dihydrobenzofurans in good yields and diastereoselectivities (up to >20:1). Use of newly developed reaction conditions that promote <i>anti</i>-heteropalladation of the alkene is essential in order to generate products in high yield. ...[more]