Ontology highlight
ABSTRACT:
SUBMITTER: Chen WT
PROVIDER: S-EPMC5383013 | biostudies-literature | 2015 Apr
REPOSITORIES: biostudies-literature
Chen Wei-Ting WT Chen Yu-Chuen YC Liou Horng-Huei HH Chao Chih-Yu CY
Scientific reports 20150421
The iron-containing hemoglobins (Hbs) are essential proteins to serve as oxygen transporters in the blood. Among various kinds of Hbs, the earthworm Hbs are the champions in carrying oxygen due to not only their large size but also the unusually high cooperativity of ligand binding. However, the cooperative oxygen binding mechanisms are still mostly unknown. Here we report the cryo-electron microscopy structure of Lumbricus terrestris Hb in its native, oxygenated state at 9.1 Å resolution, showi ...[more]