Ontology highlight
ABSTRACT:
SUBMITTER: Sun YH
PROVIDER: S-EPMC5383398 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Sun Yu Huining YH Xie Li Huitong LH Zhuo Xiaoyu X Chen Qiang Q Ghoneim Dalia D Zhang Bin B Jagne Jarra J Yang Chengbo C Li Xin Zhiguo XZ
eLife 20170406
PIWI-interacting RNAs (piRNAs) protect the germ line by targeting transposable elements (TEs) through the base-pair complementarity. We do not know how piRNAs co-evolve with TEs in chickens. Here we reported that all active TEs in the chicken germ line are targeted by piRNAs, and as TEs lose their activity, the corresponding piRNAs erode away. We observed de novo piRNA birth as host responds to a recent retroviral invasion. Avian leukosis virus (ALV) has endogenized prior to chicken domesticatio ...[more]