Ontology highlight
ABSTRACT:
SUBMITTER: Huang M
PROVIDER: S-EPMC5383578 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Huang Mingde M Hou Jiakai J Wang Yunfei Y Xie Min M Wei Chenchen C Nie Fengqi F Wang Zhaoxia Z Sun Ming M
Molecular therapy : the journal of the American Society of Gene Therapy 20170215 4
Long noncoding RNAs (lncRNAs) have emerged as important regulators in a variety of human diseases, including cancers. However, the biological function of these molecules and the mechanisms responsible for their alteration in gastric cancer (GC) are not fully understood. In this study, we found that lncRNA LINC00673 is significantly upregulated in gastric cancer. Knockdown of LINC00673 inhibited cell proliferation and invasion and induced cell apoptosis, whereas LINC00673 overexpression had the o ...[more]