Ontology highlight
ABSTRACT:
SUBMITTER: Blom RAM
PROVIDER: S-EPMC5383731 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Blom Rebecca A M RAM Amacker Mario M van Dijk R Maarten RM Moser Christian C Stumbles Philip A PA Blank Fabian F von Garnier Christophe C
Frontiers in immunology 20170407
Pulmonary administration of biomimetic nanoparticles loaded with antigen may represent an effective strategy to directly modulate adaptive immune responses in the respiratory tract. Depending on the design, virosomes may not only serve as biomimetic antigen carriers but are also endowed with intrinsic immune-stimulatory properties. We designed fluorescently labeled influenza-derived virosomes and liposome controls coupled to the model antigen ovalbumin to investigate uptake, phenotype changes, a ...[more]