Genome Sequence of the Fungal Strain 14919 Producing 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase Inhibitor FR901512.
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ABSTRACT:
SUBMITTER: Itoh H
PROVIDER: S-EPMC5383895 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
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Genome Sequence of the Fungal Strain 14919 Producing 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase Inhibitor FR901512.
Itoh Hiroya H Matsui Makoto M Kumagai Toshitaka T Arita Masanori M Machida Masayuki M Shibata Takashi T
Genome announcements 20170406 14
Fungal strain 14919 was originally isolated from a soil sample collected at Mt. Kiyosumi, Chiba Prefecture, Japan. It produces FR901512, a potent and strong 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitor. The genome sequence of fungal strain 14919 was determined and annotated to improve the productivity of FR901512. ...[more]
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