Ontology highlight
ABSTRACT:
SUBMITTER: Zhang H
PROVIDER: S-EPMC5384221 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Zhang Honglu H Chao Jie J Pan Dun D Liu Huajie H Qiang Yu Y Liu Ke K Cui Chengjun C Chen Jianhua J Huang Qing Q Hu Jun J Wang Lianhui L Huang Wei W Shi Yongyong Y Fan Chunhai C
Nature communications 20170406
Variations on DNA sequences profoundly affect how we develop diseases and respond to pathogens and drugs. Atomic force microscopy (AFM) provides a nanomechanical imaging approach for genetic analysis with nanometre resolution. However, unlike fluorescence imaging that has wavelength-specific fluorophores, the lack of shape-specific labels largely hampers widespread applications of AFM imaging. Here we report the development of a set of differentially shaped, highly hybridizable self-assembled DN ...[more]