OncoScore: a novel, Internet-based tool to assess the oncogenic potential of genes.
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ABSTRACT:
SUBMITTER: Piazza R
PROVIDER: S-EPMC5384236 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Publications
OncoScore: a novel, Internet-based tool to assess the oncogenic potential of genes.
Piazza Rocco R Ramazzotti Daniele D Spinelli Roberta R Pirola Alessandra A De Sano Luca L Ferrari Pierangelo P Magistroni Vera V Cordani Nicoletta N Sharma Nitesh N Gambacorti-Passerini Carlo C
Scientific reports 20170407
The complicated, evolving landscape of cancer mutations poses a formidable challenge to identify cancer genes among the large lists of mutations typically generated in NGS experiments. The ability to prioritize these variants is therefore of paramount importance. To address this issue we developed OncoScore, a text-mining tool that ranks genes according to their association with cancer, based on available biomedical literature. Receiver operating characteristic curve and the area under the curve ...[more]
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