Ontology highlight
ABSTRACT:
SUBMITTER: Davies MA
PROVIDER: S-EPMC5384719 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
Davies Mary-Ann MA Ford Nathan N Rabie Helena H Fatti Geoffrey G Stinson Kathryn K Giddy Janet J Tanser Frank F Technau Karl-Günter KG Sawry Shobna S Eley Brian B Wood Robin R Mofenson Lynne M LM Keiser Olivia O Boulle Andrew A
The Pediatric infectious disease journal 20151201 12
<h4>Background</h4>Ongoing CD4 monitoring in patients on antiretroviral therapy (ART) with viral suppression has been questioned. We evaluated the probability of CD4 decline in children with viral suppression and CD4 recovery after 1 year on ART.<h4>Methods</h4>We included children from 8 South African cohorts with routine HIV-RNA monitoring if (1) they were "responders" [HIV-RNA < 400 copies/mL and no severe immunosuppression after ≥1 year on ART (time 0)] and (2) ≥1 HIV-RNA and CD4 measurement ...[more]