Ontology highlight
ABSTRACT:
SUBMITTER: Koronowicz AA
PROVIDER: S-EPMC5385215 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
PPAR research 20170326
In our previous study, we showed that fatty acids from CLA-enriched egg yolks (EFA-CLA) reduced the proliferation of breast cancer cells; however, the molecular mechanisms of their action remain unknown. In the current study, we used MCF-7 breast cancer cell line to determine the effect of EFA-CLA, as potential ligands for peroxisome proliferator-activated receptors (PPARs), on identified in silico PPAR-responsive genes: <i>BCAR3</i>, <i>TCF20</i>, <i>WT1</i>, <i>ZNF621</i>, and <i>THRB</i> (tra ...[more]