Current Status of Dengue Therapeutics Research and Development.
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ABSTRACT:
SUBMITTER: Low JG
PROVIDER: S-EPMC5388029 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Publications
Current Status of Dengue Therapeutics Research and Development.
Low Jenny G H JG Ooi Eng Eong EE Vasudevan Subhash G SG
The Journal of infectious diseases 20170301 suppl_2
Dengue is a significant global health problem. Even though a vaccine against dengue is now available, which is a notable achievement, its long-term protective efficacy against each of the 4 dengue virus serotypes remains to be definitively determined. Consequently, drugs directed at the viral targets or critical host mechanisms that can be used safely as prophylaxis or treatment to effectively ameliorate disease or reduce disease severity and fatalities are still needed to reduce the burden of d ...[more]
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