Major determinants for the selecting antithrombotic therapies in patients with nonvalvular atrial fibrillation in Japan (JAPAF study).

ABSTRACT:

Background

Oral anticoagulants (OACs) can help prevent stroke in patients with nonvalvular atrial fibrillation (NVAF). The aim of this study was to characterize the use of OACs other than direct thrombin inhibitors (DTIs) for NVAF.

Methods

Patients with NVAF taking antithrombotics other than DTIs were enrolled in this cross-sectional study. Patient demographics and medication history were collected, and the patients were classified as taking antiplatelet monotherapy (AP), anticoagulant monotherapy (AC), or combination therapy (AP+AC). OAC users were also stratified as naïve (N; initiated within 6 months), switcher (S; switched within 6 months), or prevalent user (P; continued for >6 months).

Results

A total of 3053 patients (AP, 216; AC, 2381; AP+AC, 456) from 268 sit

SUBMITTER: Kusakawa K 

PROVIDER: S-EPMC5388034 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature