Ontology highlight
ABSTRACT:
SUBMITTER: Deyati A
PROVIDER: S-EPMC5389028 | biostudies-literature | 2015 Jan
REPOSITORIES: biostudies-literature
Deyati Avisek A Bagewadi Shweta S Senger Philipp P Hofmann-Apitius Martin M Novac Natalia N
Scientific reports 20150127
miRNA plays an important role in tumourgenesis by regulating expression of oncogenes and tumour suppressors. Thus affects cell proliferation and differentiation, apoptosis, invasion and angiogenesis. miRNAs are potential biomarkers for diagnosis, prognosis and therapies of different forms of cancer. However, relationship between response of cancer patients towards targeted therapy and the resulting modifications of the miRNA transcriptome in the context of pathway regulation is poorly understood ...[more]