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ISEcp1B-mediated transposition of blaCTX-M in Escherichia coli.


ABSTRACT: Several expanded-spectrum beta-lactamase bla(CTX-M) genes are associated with ISEcp1-like elements in Enterobacteriaceae. We found that ISEcp1B was able to mobilize the adjacent bla(CTX-M-19) gene by a transpositional mechanism in Escherichia coli by recognizing a variety of DNA sequences as right inverted repeats.

SUBMITTER: Poirel L 

PROVIDER: S-EPMC538921 | biostudies-literature | 2005 Jan

REPOSITORIES: biostudies-literature

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ISEcp1B-mediated transposition of blaCTX-M in Escherichia coli.

Poirel Laurent L   Lartigue Marie-Frédérique MF   Decousser Jean-Winoc JW   Nordmann Patrice P  

Antimicrobial agents and chemotherapy 20050101 1


Several expanded-spectrum beta-lactamase bla(CTX-M) genes are associated with ISEcp1-like elements in Enterobacteriaceae. We found that ISEcp1B was able to mobilize the adjacent bla(CTX-M-19) gene by a transpositional mechanism in Escherichia coli by recognizing a variety of DNA sequences as right inverted repeats. ...[more]

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