Ontology highlight
ABSTRACT:
SUBMITTER: Mukai T
PROVIDER: S-EPMC5389517 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Mukai Takahito T Vargas-Rodriguez Oscar O Englert Markus M Tripp H James HJ Ivanova Natalia N NN Rubin Edward M EM Kyrpides Nikos C NC Söll Dieter D
Nucleic acids research 20170301 5
We report the identification of novel tRNA species with 12-base pair amino-acid acceptor branches composed of longer acceptor stem and shorter T-stem. While canonical tRNAs have a 7/5 configuration of the branch, the novel tRNAs have either 8/4 or 9/3 structure. They were found during the search for selenocysteine tRNAs in terabytes of genome, metagenome and metatranscriptome sequences. Certain bacteria and their phages employ the 8/4 structure for serine and histidine tRNAs, while minor cystein ...[more]