Ontology highlight
ABSTRACT:
SUBMITTER: Le Rhun A
PROVIDER: S-EPMC5389636 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Le Rhun Anaïs A Lécrivain Anne-Laure AL Reimegård Johan J Proux-Wéra Estelle E Broglia Laura L Della Beffa Cristina C Charpentier Emmanuelle E
Nucleic acids research 20170301 5
A better understanding of transcriptional and post-transcriptional regulation of gene expression in bacteria relies on studying their transcriptome. RNA sequencing methods are used not only to assess RNA abundance but also the exact boundaries of primary and processed transcripts. Here, we developed a method, called identification of specific cleavage position (ISCP), which enables the identification of direct endoribonuclease targets in vivo by comparing the 5΄ and 3΄ ends of processed transcri ...[more]