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Truncated internalin A and asymptomatic Listeria monocytogenes carriage: in vivo investigation by allelic exchange.


ABSTRACT: Allelic exchange of the region coding for the C terminus of InlA between one epidemic (with an 80-kDa InlA) and one asymptomatic (with a 47-kDa InlA) carriage Listeria monocytogenes strain confirmed the need for this region for internalin entry in vitro. Interestingly, restoration of internalin A functionality did not result in full virulence in chicken embryo assays.

SUBMITTER: Olier M 

PROVIDER: S-EPMC538994 | biostudies-literature | 2005 Jan

REPOSITORIES: biostudies-literature

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Truncated internalin A and asymptomatic Listeria monocytogenes carriage: in vivo investigation by allelic exchange.

Olier Maïwenn M   Garmyn Dominique D   Rousseaux Sandrine S   Lemaître Jean-Paul JP   Piveteau Pascal P   Guzzo Jean J  

Infection and immunity 20050101 1


Allelic exchange of the region coding for the C terminus of InlA between one epidemic (with an 80-kDa InlA) and one asymptomatic (with a 47-kDa InlA) carriage Listeria monocytogenes strain confirmed the need for this region for internalin entry in vitro. Interestingly, restoration of internalin A functionality did not result in full virulence in chicken embryo assays. ...[more]

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