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Fluorinated polyurethane scaffolds for 19F magnetic resonance imaging.

ABSTRACT: Polymers are increasingly employed in implant materials. To reduce the incidence of complications, which in the case of vascular grafts include incorrect placement and restenosis, materials are needed which allow for image-guided implantation, as well as for accurate and efficient postoperative implant imaging. We here describe amorphous fluorinated polymers based on thermoplastic polyurethane (19F-TPU), and show that are useful starting materials for developing tissue-engineered vascular grafts which can be detected using 19F MRI.

SUBMITTER: Lammers T

PROVIDER: S-EPMC5390858 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature

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Fluorinated polyurethane scaffolds for 19F magnetic resonance imaging.

Lammers Twan T Mertens Marianne E ME Schuster Philipp P Rahimi Khosrow K Shi Yang Y Schulz Volkmar V Kuehne Alexander J C AJC Jockenhoevel Stefan S Kiessling Fabian F

Chemistry of materials : a publication of the American Chemical Society 20170401 7

Polymers are increasingly employed in implant materials. To reduce the incidence of complications, which in the case of vascular grafts include incorrect placement and restenosis, materials are needed which allow for image-guided implantation, as well as for accurate and efficient postoperative implant imaging. We here describe amorphous fluorinated polymers based on thermoplastic polyurethane (19F-TPU), and show that are useful starting materials for developing tissue-engineered vasc ...[more]

PMID: 28413258

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