Ontology highlight
ABSTRACT:
SUBMITTER: Gonzalez GM
PROVIDER: S-EPMC5393179 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Gonzalez Grecia M GM Hardwick Steven W SW Maslen Sarah L SL Skehel J Mark JM Holmqvist Erik E Vogel Jörg J Bateman Alex A Luisi Ben F BF Broadhurst R William RW
RNA (New York, N.Y.) 20170213 5
The protein ProQ has recently been identified as a global small noncoding RNA-binding protein in <i>Salmonella</i>, and a similar role is anticipated for its numerous homologs in divergent bacterial species. We report the solution structure of <i>Escherichia coli</i> ProQ, revealing an N-terminal FinO-like domain, a C-terminal domain that unexpectedly has a Tudor domain fold commonly found in eukaryotes, and an elongated bridging intradomain linker that is flexible but nonetheless incompressible ...[more]