Chronic demyelination-induced seizures.
Ontology highlight
ABSTRACT:
SUBMITTER: Lapato AS
PROVIDER: S-EPMC5394933 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Publications
Chronic demyelination-induced seizures.
Lapato Andrew S AS Szu Jenny I JI Hasselmann Jonathan P C JPC Khalaj Anna J AJ Binder Devin K DK Tiwari-Woodruff Seema K SK
Neuroscience 20170130
Multiple sclerosis (MS) patients are three to six times more likely to develop epilepsy compared to the rest of the population. Seizures are more common in patients with early onset or progressive forms of the disease and prognosticate rapid progression to disability and death. Gray matter atrophy, hippocampal lesions, interneuron loss, and elevated juxtacortical lesion burden have been identified in MS patients with seizures; however, translational studies aimed at elucidating the pathophysiolo ...[more]
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