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Fish and fish-liver oil consumption in adolescence and midlife and risk of CHD in older women.

ABSTRACT: OBJECTIVE:To study the association of fish and fish-liver oil consumption across the lifespan with CHD later in life among Icelandic women, with special emphasis on the effects of consumption in adolescence. DESIGN:Prevalence association study. Logistic regression was used to estimate odds ratios and 95 % confidence intervals of CHD according to fish or fish-liver oil exposure. Models were adjusted for age, education, concurrent diet and other known risk factors. SETTING:The study was nested within the AGES-Reykjavik Study, conducted in Reykjavik, Iceland. SUBJECTS:Participants were 3326 women aged 66-96 years, with available information on CHD status at entry to the study and information on fish and fish-liver oil consumption during midlife and adolescence. Dietary habits were assessed retrospectively using a validated FFQ. RESULTS:CHD was identified in 234 (7·9 %) women. Compared with women with no intake of fish-liver oil in adolescence or midlife, women who consumed fish-liver oil at least three times weekly in adolescence or in midlife had a decreased risk of CHD (OR=0·62; 95 % CI 0·45, 0·85 and OR=0·68; 95 % CI 0·50, 0·94, respectively). No associations were observed between fish intake (>2 portions/week v. ?2 portions/week) in adolescence or midlife and CHD in this population with high fish intake. CONCLUSIONS:Fish-liver oil consumption, from early life, may reduce the risk of CHD in older women. Lifelong nutrition may be of importance in the prevention of CHD in older women.

SUBMITTER: Haraldsdottir A

PROVIDER: S-EPMC5395091 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature

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Fish and fish-liver oil consumption in adolescence and midlife and risk of CHD in older women.

Haraldsdottir Alfheidur A Torfadottir Johanna E JE Valdimarsdottir Unnur A UA Aspelund Thor T Harris Tamara B TB Launer Lenore J LJ Gudnason Vilmundur V Steingrimsdottir Laufey L

Public health nutrition 20150417 2

<h4>Objective</h4>To study the association of fish and fish-liver oil consumption across the lifespan with CHD later in life among Icelandic women, with special emphasis on the effects of consumption in adolescence.<h4>Design</h4>Prevalence association study. Logistic regression was used to estimate odds ratios and 95 % confidence intervals of CHD according to fish or fish-liver oil exposure. Models were adjusted for age, education, concurrent diet and other known risk factors.<h4>Setting</h4>Th ...[more]

PMID: 25882499

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Dataset Information

Fish and fish-liver oil consumption in adolescence and midlife and risk of CHD in older women.

Publications

Fish and fish-liver oil consumption in adolescence and midlife and risk of CHD in older women.

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