Ontology highlight
ABSTRACT:
SUBMITTER: Zhang Y
PROVIDER: S-EPMC5396547 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Zhang Yaping Y Hu Kaiqiang K Beumer Jan H JH Bakkenist Christopher J CJ D'Argenio David Z DZ
DNA repair 20170220
We present a comprehensive software program, RAD-ADAPT, for the quantitative analysis of clonogenic assays in radiation biology. Two commonly used models for clonogenic assay analysis, the linear-quadratic model and single-hit multi-target model, are included in the software. RAD-ADAPT uses maximum likelihood estimation method to obtain parameter estimates with the assumption that cell colony count data follow a Poisson distribution. The program has an intuitive interface, generates model predic ...[more]