Ontology highlight
ABSTRACT:
SUBMITTER: Arnold LE
PROVIDER: S-EPMC5397211 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Arnold L Eugene LE Young Andrea S AS Belury Martha A MA Cole Rachel M RM Gracious Barbara B Seidenfeld Adina M AM Wolfson Hannah H Fristad Mary A MA
Journal of child and adolescent psychopharmacology 20170203 3
<h4>Objective</h4>To examine fatty acid profiles, their response to omega-3 fatty acid (Ω3) supplementation, and associations with clinical status and treatment response in youth with mood disorders.<h4>Methods</h4>In a placebo-controlled 2X2 design, 7-14 year-olds (N = 95) in parallel pilot trials (depression N = 72; bipolar N = 23) were randomly assigned to 12 weeks of Ω3 supplementation (1.4 g eicosapentaenoic acid [EPA], 0.2 g docosahexaenoic acid [DHA], and 0.27 g other Ω3 per day); psychoe ...[more]