Ontology highlight
ABSTRACT:
SUBMITTER: Chen S
PROVIDER: S-EPMC5397487 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Chen Shilong S Wang Long L Chen Jieying J Zhang Lanlan L Wang Song S Goraya Mohsan U MU Chi Xiaojuan X Na Yang Y Shao Wenhan W Yang Zhou Z Zeng Xiancheng X Chen Shaoying S Chen Ji-Long JL
Frontiers in microbiology 20170420
Avian Tembusu virus (ATMUV) is a highly pathogenic flavivirus that causes significant economic losses to the Chinese poultry industry. Our previous experiments demonstrated that ATMUV infection effectively triggered host innate immune response through MDA5 and TLR3-dependent signaling pathways. However, little information is available on the role of interferon-stimulated genes (ISGs) in defending against ATMUV infection. In this study, we found that ATMUV infection induced robust expression of t ...[more]