Dataset Information

Accuracy of low-density lipoprotein cholesterol estimation at very low levels.

ABSTRACT: As the approach to low-density lipoprotein cholesterol (LDL-C) lowering becomes increasingly intensive, accurate assessment of LDL-C at very low levels warrants closer attention in individualized clinical efficacy and safety evaluation. We aimed to assess the accuracy of LDL-C estimation at very low levels by the Friedewald equation, the de facto clinical standard, and compare its accuracy with a novel, big data-derived LDL-C estimate.In 191,333 individuals with Friedewald LDL-C?

SUBMITTER: Quispe R

PROVIDER: S-EPMC5399386 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature

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Accuracy of low-density lipoprotein cholesterol estimation at very low levels.

Quispe Renato R Hendrani Aditya A Elshazly Mohamed B MB Michos Erin D ED McEvoy John W JW Blaha Michael J MJ Banach Maciej M Kulkarni Krishnaji R KR Toth Peter P PP Coresh Josef J Blumenthal Roger S RS Jones Steven R SR Martin Seth S SS

BMC medicine 20170420 1

<h4>Background</h4>As the approach to low-density lipoprotein cholesterol (LDL-C) lowering becomes increasingly intensive, accurate assessment of LDL-C at very low levels warrants closer attention in individualized clinical efficacy and safety evaluation. We aimed to assess the accuracy of LDL-C estimation at very low levels by the Friedewald equation, the de facto clinical standard, and compare its accuracy with a novel, big data-derived LDL-C estimate.<h4>Methods</h4>In 191,333 individuals wit ...[more]

PMID: 28427464

Dataset Information

Accuracy of low-density lipoprotein cholesterol estimation at very low levels.

Publications

Accuracy of low-density lipoprotein cholesterol estimation at very low levels.

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