Ontology highlight
ABSTRACT:
SUBMITTER: Theofel I
PROVIDER: S-EPMC5399552 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Theofel Ina I Bartkuhn Marek M Boettger Thomas T Gärtner Stefanie M K SMK Kreher Judith J Brehm Alexander A Rathke Christina C
Biology open 20170415 4
Male germ cell differentiation proceeds to a large extent in the absence of active gene transcription. In <i>Drosophila</i>, hundreds of genes whose proteins are required during post-meiotic spermatid differentiation (spermiogenesis) are transcribed in primary spermatocytes. Transcription of these genes depends on the sequential action of the testis meiotic arrest complex (tMAC), Mediator complex, and testis-specific TFIID (tTFIID) complex. How the action of these protein complexes is coordinate ...[more]