Ontology highlight
ABSTRACT:
SUBMITTER: Mansilla Pareja ME
PROVIDER: S-EPMC5401879 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Mansilla Pareja María E ME Bongiovanni Antonino A Lafont Frank F Colombo María I MI
Frontiers in cellular and infection microbiology 20170424
<i>Coxiella burnetii</i>, the etiologic agent of Q fever, is a Gram-negative obligate intracellular bacterium. It has been previously described that both the endocytic and autophagic pathways contribute to the <i>Coxiella</i> replicative vacuole (CRV) generation. Galectins are β-galactoside-binding lectins that accumulate in the cytosol before being secreted via a non-conventional secretory pathway. It has been shown that Galectin-3, -8, -9 monitor bacteria vacuolar rupture and endosomal and lys ...[more]