Ontology highlight
ABSTRACT:
SUBMITTER: Fuller TW
PROVIDER: S-EPMC5402006 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Fuller Thomas W TW Jiang Xuewen X Bansal Utsav U Lamm Vladimir V Shen Bing B Wang Jicheng J Roppolo James R JR de Groat William C WC Tai Changfeng C
American journal of physiology. Regulatory, integrative and comparative physiology 20161214 3
This study investigated the role of γ-aminobutyric acid subtype B (GABA<sub>B</sub>) receptors in tibial and pudendal neuromodulation of bladder overactivity induced by intravesical administration of dilute (0.5%) acetic acid (AA) in α-chloralose-anesthetized cats. To inhibit bladder overactivity, tibial or pudendal nerve stimulation (TNS or PNS) was applied at 5 Hz and two or four times threshold (T) intensity for inducing toe or anal sphincter twitch. TNS at 2T or 4T intensity significantly (< ...[more]