Quantitative microvascular analysis of retinal venous occlusions by spectral domain optical coherence tomography angiography.

ABSTRACT:

Purpose

To quantitatively evaluate the retinal microvasculature in human subjects with retinal venous occlusions (RVO) using optical coherence tomography angiography (OCTA).

Design

Retrospective, cross-sectional, observational case series.

Participants

Sixty subjects (84 eyes) were included (20 BRVO, 14 CRVO, 24 unaffected fellow eyes, and 26 controls).

Methods

OCTA was performed on a prototype, spectral domain-OCTA system in the 3x3mm central macular region. Custom software was used to quantify morphology and density of retinal capillaries using four quantitative parameters. The vasculature of the segmented retinal layers and nonsegmented whole retina were analyzed.

Main outcome measures

Fractal dimension (FD), vessel density (VD), skeletal density (SD)

SUBMITTER: Koulisis N 

PROVIDER: S-EPMC5402954 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature