Ontology highlight
ABSTRACT:
SUBMITTER: Panagopoulos I
PROVIDER: S-EPMC5403202 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Panagopoulos Ioannis I Gorunova Ludmila L Torkildsen Synne S Tierens Anne A Heim Sverre S Micci Francesca F
Oncology letters 20170208 4
RNA-sequencing of the patient's bone marrow detected fusion transcripts in which the coding sequence of the <i>FAM53B</i> gene (from 10q26) was fused to a genomic sequence (from 19q13) that mapped upstream of the <i>SLC7A10</i> locus. Reverse transcription-polymerase chain reaction together with Sanger sequencing verified the presence of this fusion transcript. The <i>FAM53B</i> fusion transcript is not expected to produce any chimeric protein. However, it may code for a truncated FAM53B protein ...[more]