Dataset Information

Prevalence and correlates of vaginal estrogenization in postmenopausal women in the United States.

ABSTRACT: OBJECTIVE:This work aims to establish current population-based vaginal estrogenization norms for postmenopausal US women. METHODS:Using a US national probability sample of 868 postmenopausal women ages 57 to 85 years (mean age 67.6?±?0.3 y, 21.6?±?0.5 y since menopause), we calculated the epithelial maturation value (MV) generated from self-collected vaginal specimens and compared findings with historical clinical data. Linear and logistic regressions were used to describe the relationship between vaginal estrogenization and sociodemographic, physical, gynecologic, and sexual characteristics. RESULTS:Among postmenopausal women, mean MV was 46.6?±?0.8 (SD 17.4, range 2.5-100) and stable across age groups. In every age group, vaginal estrogenization was higher among postmenopausal nonusers of hormone therapy (HT) in the 2005-2006 US cohort than reported for the 1960s Canadian clinical cohort. MV was also higher among women who used postmenopausal HT in the prior 12 months compared with those who did not (55.1?±?1.2 vs 44.4?±?0.9, P?

SUBMITTER: Lindau ST

PROVIDER: S-EPMC5403603 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature

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Prevalence and correlates of vaginal estrogenization in postmenopausal women in the United States.

Lindau Stacy Tessler ST Dude Annie A Gavrilova Natalia N Hoffmann Joscelyn N JN Schumm L Philip LP McClintock Martha K MK

Menopause (New York, N.Y.) 20170501 5

<h4>Objective</h4>This work aims to establish current population-based vaginal estrogenization norms for postmenopausal US women.<h4>Methods</h4>Using a US national probability sample of 868 postmenopausal women ages 57 to 85 years (mean age 67.6 ± 0.3 y, 21.6 ± 0.5 y since menopause), we calculated the epithelial maturation value (MV) generated from self-collected vaginal specimens and compared findings with historical clinical data. Linear and logistic regressions were used to describe the rel ...[more]

PMID: 27898651

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Project description:Background and objectivesThe prevalence of ESRD among Hispanics/Latinos is 2-fold higher than in non-Hispanic whites. However, little is known about the prevalence of earlier stages of CKD among Hispanics/Latinos. This study estimated the prevalence of CKD in US Hispanics/Latinos.Design, setting, participants, & measurementsThis was a cross-sectional study of 15,161 US Hispanic/Latino adults of Cuban, Dominican, Mexican, Puerto Rican, Central American, and South American backgrounds enrolled in the multicenter, prospective, population-based Hispanic Community Health Study/Study of Latinos (HCHS/SOL). In addition, the prevalence of CKD in Hispanics/Latinos was compared with other racial/ethnic groups in the 2007-2010 National Health and Nutrition Examination Survey (NHANES). Prevalent CKD was defined as an eGFR <60 ml/min per 1.73 m(2) (estimated with the 2012 Chronic Kidney Disease Epidemiology Collaboration eGFR creatinine-cystatin C equation) or albuminuria based on sex-specific cut points determined at a single point in time.ResultsThe overall prevalence of CKD among Hispanics/Latinos was 13.7%. Among women, the prevalence of CKD was 13.0%, and it was lowest in persons with South American background (7.4%) and highest (16.6%) in persons with Puerto Rican background. In men, the prevalence of CKD was 15.3%, and it was lowest (11.2%) in persons with South American background and highest in those who identified their Hispanic background as "other" (16.0%). The overall prevalence of CKD was similar in HCHS/SOL compared with non-Hispanic whites in NHANES. However, prevalence was higher in HCHS/SOL men and lower in HCHS/SOL women versus NHANES non-Hispanic whites. Low income, diabetes mellitus, hypertension, and cardiovascular disease were each significantly associated with higher risk of CKD.ConclusionsAmong US Hispanic/Latino adults, there was significant variation in CKD prevalence among Hispanic/Latino background groups, and CKD was associated with established cardiovascular risk factors.

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Dataset Information

Prevalence and correlates of vaginal estrogenization in postmenopausal women in the United States.

Publications

Prevalence and correlates of vaginal estrogenization in postmenopausal women in the United States.

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