Ontology highlight
ABSTRACT:
SUBMITTER: Nuebel E
PROVIDER: S-EPMC5404111 | biostudies-literature | 2016 Nov
REPOSITORIES: biostudies-literature
Nuebel Esther E Manganas Phanee P Tokatlidis Kostas K
Biochimica et biophysica acta 20160715 11
The mitochondrial intermembrane space (IMS) is involved in protein transport, lipid homeostasis and metal ion exchange, while further acting in signalling pathways such as apoptosis. Regulation of these processes involves protein modifications, as well as stress-induced import or release of proteins and other signalling molecules. Even though the IMS is the smallest sub-compartment of mitochondria, its redox state seems to be tightly regulated. However, the way in which this compartment particip ...[more]