Ontology highlight
ABSTRACT:
SUBMITTER: Yang YQ
PROVIDER: S-EPMC5404584 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Yang Yong-Qiang YQ Li Yun-Xia YX Song Tao T Yang Yan-Xian YX Jiang Wei W Zhang An-Yun AY Guo Xin-Yi XY Liu Bi-Hui BH Wang Yong-Xiang YX Lei Chang-Wei CW Xiang Rong R Wang Hong-Ning HN
Antimicrobial agents and chemotherapy 20170424 5
The <i>mcr-1</i> gene was detected in 5.11% (58/1136) of <i>Escherichia coli</i> isolates of chicken origin from 13 provinces in China. A novel <i>mcr-1</i> variant, named <i>mcr-1.3</i>, encoding an Ile-to-Val functional variant of MCR-1 was identified in a sequence type 155 (ST155) strain. An <i>mcr-1.3</i>-containing IncI2 plasmid, pHeN867 (60,757 bp), was identified. The transfer of pHeN867 led to a 32-fold increase in the MIC of colistin in the recipient, exhibiting an effect on colistin re ...[more]