Ontology highlight
ABSTRACT:
SUBMITTER: Ramachandran G
PROVIDER: S-EPMC5404592 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Ramachandran Geetha G Agibothu Kupparam Hemanth Kumar HK Vedhachalam Chandrasekaran C Thiruvengadam Kannan K Rajagandhi Vijayalakshmi V Dusthackeer Azger A Karunaianantham Ramesh R Jayapal Lavanya L Swaminathan Soumya S
Antimicrobial agents and chemotherapy 20170424 5
The Indian Revised National Tuberculosis (TB) Control Programme uses thrice-weekly treatment with standard drug dosages. The role of plasma drug levels and other factors in determining TB treatment outcomes is not well understood. We aimed to determine the factors influencing the concentrations of rifampin (RMP), isoniazid (INH), and pyrazinamide (PZA) at 2 h postdosing in adult TB patients and to study the factors impacting TB treatment outcome. We recruited 1,912 adult TB patients (newly treat ...[more]