Effects of Stimulus Polarity and Artifact Reduction Method on the Electrically Evoked Compound Action Potential.

ABSTRACT:

Objective

Previous research from our laboratory comparing electrically evoked compound action potential (ECAP) artifact reduction methods has shown larger amplitudes and lower thresholds with cathodic-leading forward masking (CathFM) than with alternating polarity (AltPol). One interpretation of this result is that the anodic-leading phase used with AltPol elicits a less excitatory response (in contrast to results from recent studies with humans), which when averaged with responses to cathodic-leading stimuli, results in smaller amplitudes. Another interpretation is that the latencies of the responses to anodic- and cathodic-leading pulses differ, which when averaged together, result in smaller amplitudes than for either polarity alone due to temporal smearing. The purpose of this

SUBMITTER: Hughes ML 

PROVIDER: S-EPMC5404966 | biostudies-literature | 2017 May/Jun

REPOSITORIES: biostudies-literature