Ontology highlight
ABSTRACT:
SUBMITTER: Bosi S
PROVIDER: S-EPMC5407555 | biostudies-literature | 2015 Apr
REPOSITORIES: biostudies-literature
Scientific reports 20150424
To recreate in vitro 3D neuronal circuits will ultimately increase the relevance of results from cultured to whole-brain networks and will promote enabling technologies for neuro-engineering applications. Here we fabricate novel elastomeric scaffolds able to instruct 3D growth of living primary neurons. Such systems allow investigating the emerging activity, in terms of calcium signals, of small clusters of neurons as a function of the interplay between the 2D or 3D architectures and network dyn ...[more]