Ontology highlight
ABSTRACT:
SUBMITTER: Smith LM
PROVIDER: S-EPMC5407948 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Smith L M LM Weissenburger-Moser L A LA Heires A J AJ Bailey K L KL Romberger D J DJ LeVan T D TD
Genes and immunity 20170126 2
Exposure to organic dust from agricultural environments is associated with inflammatory respiratory conditions. The putative causal agents in organic dust include viral, microbial and fungal components, which are recognized by the family of Toll-like receptors (TLRs) and drive host innate and adaptive responses. Our aim in this study was to determine whether responsiveness to organic dust among agricultural workers was dependent on polymorphisms in the TLR10-TLR1-TLR6 gene cluster. We stimulated ...[more]