Ontology highlight
ABSTRACT:
SUBMITTER: Rosner B
PROVIDER: S-EPMC5409172 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
Rosner Bernard B Tworoger Shelley S Qiu Weiliang W
Journal of biometrics & biostatistics 20151228 5
Diagnostic biomarkers are used frequently in epidemiologic and clinical work. The ability of a diagnostic biomarker to discriminate between subjects who develop disease (cases) and subjects who do not (controls) is often measured by the area under the receiver operating characteristic curve (AUC). The diagnostic biomarkers are usually measured with error. Ignoring measurement error can cause biased estimation of AUC, which results in misleading interpretation of the efficacy of a diagnostic biom ...[more]